CFL1 polyclonal antibody
产品名称： CFL1 polyclonal antibody
英文名称： CFL1 polyclonal antibody
产品编号： PAB5302
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CFL1.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding S3 of human CFL1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Detection of urine cofilin-1 from patients hospitalized in the intensive care unit using the metal-enhanced fluorescence technique.
Chao CH, Chang YF, Chen HC, Lin LY, Yu PC, Chang YS, Lee YJ.Sensors and Actuators B: Chemical (2010), doi:10.1016/ j.snb.2012.06.076
- 2.
- MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration.
Kobayashi M, Nishita M, Mishima T, Ohashi K, Mizuno K.EMBO J. 2006 Feb 22;25(4):713-26. Epub 2006 Feb 2.
- 3.
- Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin.
Wang Y, Shibasaki F, Mizuno K.J Biol Chem. 2005 Apr 1;280(13):12683-9. Epub 2005 Jan 24.
- 4.
- Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer.
Smith-Beckerman DM, Fung KW, Williams KE, Auersperg N, Godwin AK, Burlingame AL.Mol Cell Proteomics. 2005 Feb;4(2):156-68. Epub 2004 Dec 9.
- Entrez GeneID:
- 1072
- Gene Name:
- CFL1
- Gene Alias:
- CFL
- Gene Description:
- cofilin 1 (non-muscle)
- Omim ID:
- 601442
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM
- Other Designations:
- -
- Related Disease