BCCIP MaxPab mouse polyclonal antibody (B01)
产品名称： BCCIP MaxPab mouse polyclonal antibody (B01)
英文名称： BCCIP MaxPab mouse polyclonal antibody (B01)
产品编号： H00056647-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human BCCIP protein.
- Immunogen:
- BCCIP (AAH09771, 1 a.a. ~ 314 a.a) full-length human protein.
- Sequence:
- MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAEKNNSKKKPSNKKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDKMNEIMDKLKEYLSV
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of BCCIP expression in transfected 293T cell line (H00056647-T01) by BCCIP MaxPab polyclonal antibody.
Lane 1: BCCIP transfected lysate(34.54 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to BCCIP on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 56647
- GeneBank Accession#:
- BC009771
- Protein Accession#:
- AAH09771
- Gene Name:
- BCCIP
- Gene Alias:
- TOK-1,TOK1
- Gene Description:
- BRCA2 and CDKN1A interacting protein
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- BCCIPalpha,BCCIPbeta,BRCA2 and CDKN1A-interacting protein,BRCA2 and Cip1/p21 interacting protein,OTTHUMP00000020714,OTTHUMP00000020715,OTTHUMP00000020716,TOK-1alpha,TOK-1beta,cdk inhibitor p21 binding protein,p21- and CDK-associated protein 1