BRIP1 (phospho S990)polyclonal antibody
产品名称： BRIP1 (phospho S990)polyclonal antibody
英文名称： BRIP1 (phospho S990)polyclonal antibody
产品编号： PAB15895
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRIP1.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S990 of human BRIP1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:2000-1:5000)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.
Litman R, Peng M, Jin Z, Zhang F, Zhang J, Powell S, Andreassen PR, Cantor SB.Cancer Cell. 2005 Sep;8(3):255-65.
- 2.
- Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villen J, Li J, Cohn MA, Cantley LC, Gygi SP.Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12130-5. Epub 2004 Aug 9.
- 3.
- The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations.
Cantor S, Drapkin R, Zhang F, Lin Y, Han J, Pamidi S, Livingston DM.Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2357-62.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 83990
- Gene Name:
- BRIP1
- Gene Alias:
- BACH1,FANCJ,FLJ90232,MGC126521,MGC126523,OF
- Gene Description:
- BRCA1 interacting protein C-terminal helicase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq
- Other Designations:
- BRCA1-associated C-terminal helicase 1,BRCA1-binding helicase-like protein BACH1,BRCA1-interacting protein 1
- Related Disease
- Abortion, Spontaneous
- Adenocarcinoma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Transitional Cell
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- DNA Damage
- Edema
- Genetic Predisposition to Disease
- Glioma
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma
- Neoplasms
- Neoplasms, Glandular and Epithelial
- Neuroma, Acoustic