ANX1 polyclonal antibody
产品名称： ANX1 polyclonal antibody
英文名称： ANX1 polyclonal antibody
产品编号： PAB7948
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ANX1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at C-terminus of human ANX1.
- Sequence:
- QKMYGISLCQAILDETK
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR.
Walther A, Riehemann K, Gerke V.Mol Cell. 2000 May;5(5):831-40.
- 2.
- Correlation of gene and protein structure of rat and human lipocortin I.
Kovacic RT, Tizard R, Cate RL, Frey AZ, Wallner BP.Biochemistry. 1991 Sep 17;30(37):9015-21.
- 3.
- Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity.
Wallner BP, Mattaliano RJ, Hession C, Cate RL, Tizard R, Sinclair LK, Foeller C, Chow EP, Browing JL, Ramachandran KL, et al..Nature. 1986 Mar 6-12;320(6057):77-81.
- Entrez GeneID:
- 301
- Gene Name:
- ANXA1
- Gene Alias:
- ANX1,LPC1
- Gene Description:
- annexin A1
- Omim ID:
- 151690
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. [provided by RefSeq
- Other Designations:
- OTTHUMP00000021474,OTTHUMP00000021475,annexin I,annexin I (lipocortin I),lipocortin I
- Related Disease